Dental composites are now the restoration of choice for most practitioners, due to their ease of handling and superior esthetics. At the same time the actual risk of use of BisphenolA (BPA) and BPA derivatives in dental composites, their degree of elution, and BPA exposure levels remain controversial.
The objective of this review is to consider these claims, and to examine the literature on different methods to counter this potential toxicity. A search of the literature was conducted for studies focusing on BPA toxicity in dentistry, up to 5 years (January 2009). The preferred reporting items for systematic reviews were used as guideline method.
Electronic databases: PubMed and ScienceDirect were used. In addition, studies were identified by searching of selected journals. The results were examined for relevance. Criteria for selection included were toxicity assessment, chemical composition, type of cure and duration, and materials affecting toxicity.
As a conclusion, the potential toxicity of BPA and BPA derivatives in dental composites still needs to be confirmed.The reviewfocused on new methods for BPA toxicity assessment, the effect of additions like antioxidants and antimicrobials, together with new developments in dental composite chemical formulations, especially the monomer chemistry, and their effect in countering BPA toxicity in vitro. Overall, a more complete and comprehensive analysis is required, further studies are needed to fully acknowledge these conclusions in vivo and clinical situation.
Bisphenol A, Toxicity, Restorative materials, Dental